Journal of Psychopharmacology
- Validating and creating a short-form of the persisting effects questionnaire: A measure of positive and negative outcomes from psychedelic experiences5 days ago
- Defining the intervention before estimating efficacy in DMT-assisted therapy6 days ago
- Adjunctive GLP-1 receptor agonists for cardiometabolic risk in antipsychotic-treated patients: A GRADE-assessed meta-analysis of randomized trials7 days ago
- Psychedelic therapy without durable effects: A review and re-evaluation of controlled studies between 1965 and 19772 weeks ago
- The effect of ketamine on mitochondrial bioenergetics, viability, and function: A systematic review2 weeks ago
- Psilocybin-induced changes in electroencephalography link acute and long-term effects3 weeks ago
- Safety, pharmacokinetics, and pharmacodynamics of intravenously administered deuterated N,N-dimethyltryptamine (CYB004) in healthy volunteers3 weeks ago
- Safety, tolerability and pharmacokinetics of an NMDA receptor subunit 2B-selective negative allosteric modulator, BI 1569912: Results of three partially randomised, placebo-controlled phase I trials3 weeks ago
- Reinstatement of escitalopram and clonidine administration reverses the cessation-induced enhanced activation of rat norepinephrine and serotonin neuronal firing activity3 weeks ago
- A novel approach for evaluating and comparing multiple antipsychotic polypharmacy in adults across specialist intellectual disability services in England and Wales: A retrospective feasibility cohort study3 weeks ago
- Differential effects of psilocybin derivatives on fentanyl-induced conditioned place preference in male and female mice3 weeks ago
- Pharmacokinetics, pharmacodynamics and safety of N,N-dimethyltryptamine administered intravenously in healthy smoking and non-smoking volunteers3 weeks ago
- A randomized crossover trial comparing the acute physiological and psychological effects of botanical formulations of oral psilocybin, oral psilocin, and sublingual psilocin3 weeks ago
- Oregon’s state-regulated psilocybin services: Early real-world safety signals4 weeks ago
- Beyond head-twitch response: Acute psilocybin affects spontaneous behaviors in rats in a dose-dependent manner4 weeks ago
- Dopaminergic fronto-striatal connectivity underlies schema-dependent learning4 weeks ago
- Benzodiazepines and GABAA receptor subtypes: Effects in open-field, elevated plus maze-discriminative avoidance task, and conditioned place preference in male mice4 weeks ago
- Salvinorin A in humans: A systematic review of pharmacokinetics, pharmacodynamics, and safety4 weeks ago
- Psilocybin-assisted psychotherapy for substance use disorders as a complex intervention: A systematic review of efficacy, mechanisms and psychotherapeutic frameworks1 month ago
- Experience, plasticity, and context: Beyond single-level models of antidepressant action1 month ago
- Defining ‘psychedelic’1 month ago
- What are the clinical implications of mixed features in major depressive disorder? A VAST-D report1 month ago
- AUT00206, a novel and selective Kv3.1/3.2 channel modulator, restores cognitive dysfunction and negative symptoms in an animal model for schizophrenia symptomatology1 month ago
- Impact of adjunctive dihydropyridine calcium channel blockers on mental health outcomes in people with severe mental illness: A target trial emulation in English electronic health records1 month ago
- Psychotropic medication prescribing to children and young people mental health inpatient services: An English national study1 month ago
- The occurrence and potential role of mystical experiences in MDMA-assisted therapy for PTSD: A secondary analysis2 months ago
- Lithium toxicity from angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker co-prescription: A population-based cohort study2 months ago
- CB1 receptor-enriched functional connectivity analysis revealed target-specific modulation by cannabidiol in early psychosis2 months ago
- A pharmacometric framework for norepinephrine transporter occupancy and dose equivalence across psychotropic medications2 months ago
- Where is the sweet spot for psychedelic-enhanced fear extinction? An integrative quantitative synthesis of dose–effect patterns in rodent models2 months ago
- Clarifying age filtering in a TriNetX-based study on pediatric antidepressant use and treatment-emergent mania2 months ago
- The role of aripiprazole in modulating putamen and thalamus functional connectivity in early psychosis patients2 months ago
- Mediators of treatment response in a clinical trial of naltrexone and bupropion for methamphetamine use disorder: A longitudinal mediation analysis2 months ago
- Genetic background and sex moderate the effects of adolescent nicotine exposure on adult functional neural circuits and behavior2 months ago
- No evidence for deleterious effects of psilocybin and MDMA on working memory or related neurophysiological activity in a non-clinical population: An uncontrolled exploratory study2 months ago
- Silence is golden: Documenting the speech production of participants and support providers in psilocybin administration sessions for the treatment of post-traumatic stress disorder2 months ago
- The increasing use of cognitive enhancing drugs by those with ADHD and neurotypical individuals: Societal demands, lifestyle preferences, and ethical issues2 months ago
- Acute behavioural effects of low-dose cannabidiol: A randomised crossover trial in healthy volunteers2 months ago
- Enhancing plasticity to treat depression and other central nervous system diseases using event-driven pharmacology2 months ago
- Beyond symptom reduction: DMT improves anxiety, life satisfaction, and quality of life in healthy volunteers and patients with depression3 months ago
- Caution in interpreting value-related change after psilocybin: Comment on Kerr-Gaffney et al. (2026)3 months ago
- Effects of antidepressants, anesthetics and sedatives/hypnotics on sleep-associated memory consolidation – A systematic review3 months ago
- Mental resilience is not meaningfully associated with the frequency and severity of alcohol hangover3 months ago
- Classical psychedelic microdosing, mood, and cognitive function: An umbrella review with narrative synthesis3 months ago
- Psilocybin reduces fear memory and restores neuroplasticity in the hippocampus and medial prefrontal cortex3 months ago
- The purpose of the psychosocial protocol in the psychedelic-assisted therapy: A scoping review3 months ago
- Mitochondrial dysfunction in schizophrenia and its modulation by atypical antipsychotic drugs: A randomized controlled trial3 months ago
- Effects of pimavanserin, xanomeline and highly-purified plant-derived cannabidiol on MK-801-induced behaviours in mice relevant to psychosis3 months ago
- The intersection between psychedelics and schizophrenia spectrum disorders: Reevaluating risk and therapeutic potential3 months ago
- Pharmacokinetics and pharmacodynamics of orally administered S-ketamine in healthy participants3 months ago
- Angiotensin II and angiotensin-(1–7) neurotransmissions in the medial amygdala differently control cardiovascular and anxiogenic-like responses to stress in rats3 months ago
- A noninvasive approach to modeling cocaine self-administration in mice3 months ago
- Evaluating the abuse liability of ketamine in the treatment of mood disorders: A systematic review3 months ago
- Enhanced cognitive protection through the combination of Amylovis-201, an anti-amyloidogenic agent with sigma-1 receptor agonist activity, and environmental enrichment in mice3 months ago
- Blocking 5-HT2B receptors abolishes psilocybin’s efficacy in the rat forced swim test3 months ago
- Prenatal cannabis use is associated with altered miRNA and protein expression in the developing human brain3 months ago
- Effects of glucagon-like peptide-1 receptor agonists on anthropometric and adiposity measures in patients with antipsychotic-induced weight gain: A systematic review and meta-analysis3 months ago
- The renin angiotensin system in cognitive flexibility: Effects of single-dose losartan on task-switching in healthy volunteers3 months ago
- Ten practical suggestions for setting up a psychedelic study3 months ago
- Classic psychedelics and personality: An updated systematic review4 months ago
- Clozapine-induced neutropenia: Prevalence and associated factors4 months ago
- Effects of psilocybin on sleep quality and brain microstructure in chronic cluster headache4 months ago
- A systematic review of the pharmacokinetics of classical serotonergic psychedelic compounds in healthy adult subjects4 months ago
- Mechanistic insights into the safety of daridorexant in older adults: From postural stability to next-day function4 months ago
- Speech markers of psychological change following a psychedelic 5-MeO-DMT retreat4 months ago
- Dynamic excitatory-inhibitory differences in autistic and non-autistic adults: Evidence from a pharmacological challenge with arbaclofen4 months ago
- Methylphenidate and manic relapse in bipolar disorders: A replication study in a nationwide claims database4 months ago
- Electrophysiological correlates of resisting craving in adults with tobacco use disorders4 months ago
- From monotherapy to sequential models: An updated scoping review on ibogaine’s role in treatment for psychiatric disorders4 months ago
- Neurocognitive changes in lithium-treated older adult bipolar patients on antipsychotics4 months ago
- Associations between psychedelic use and migraine history in Swedish twins4 months ago
- The goal of specificity in psychotropic drug development: A lesson from Sisyphus?5 months ago
- Efficacy of pharmacological and nutritional interventions for glucose dysfunction in schizophrenia—A systematic review and network meta-analysis5 months ago
- Oxytocin prevents ketamine-induced executive control deficits in macaque monkeys5 months ago
- Cardiovascular mortality and depression: A systematic review and meta-analysis of the association with antidepressant treatment and co-morbidity5 months ago
- Effects of benzodiazepines on saccadic eye movements: A systematic review and meta-analysis5 months ago
- 5-HT1A receptor blockade potentiates the subjective effects of DMT5 months ago
- Effects of psychedelic use on authoritarian attitudes revisited5 months ago
- Preliminary evidence that serum interleukin-6 is a candidate biomarker of response to esketamine in treatment-resistant depression5 months ago
- The effects of the PDE4 inhibitor roflumilast on cognitive performance after a cerebrovascular accident: a double-blind randomized placebo-controlled trial with an open label extension (ROSTMEMA)5 months ago
- Substance use predictors of arrest and self-reported criminal behavior in the United States: The role of psychedelics and rarely used drugs5 months ago
- Mismatch negativity in patients with bipolar affective disorder: a systematic review and meta-analysis5 months ago
- Comparison of average time-to-relapse following ECT versus ketamine – A systematic review5 months ago
- Efficacy of N, N-dimethyltryptamine (DMT) psychedelic therapy for substance misuse: A systematic review and meta-analysis5 months ago
- Cannabidiol for psychotic disorders: A meta-analysis of randomized controlled trials6 months ago
- Nathan S. Kline: From the first treatments of psychosis and depression, a 70-year legacy of a pioneer of psychopharmacology6 months ago
- The impact of antidepressant use on MDMA fatalities: A matched case-control study using a post-mortem database6 months ago
- Antipsychotic action and symptom specificity – down the bioinformatic rabbit hole6 months ago
- The unique efficacy of clozapine is attributable to muscarinic receptor agonism6 months ago
- The behavioural effects of the serotonin 1A receptor agonist buspirone on reward processing in healthy volunteers: A randomised, placebo-controlled study6 months ago
- Administration of an extrasynaptic δ-subunit GABAA receptor agonist in the prelimbic cortex attenuates methamphetamine sensitisation and relapse to methamphetamine-seeking behaviour in male rats6 months ago
- Trip killers: Addressing a critical knowledge gap in psychedelic research6 months ago
- Effects of acute alcohol consumption on hostile attribution bias towards emotional facial expressions and implicit approach/avoidance tendencies6 months ago
- Esketamine nasal spray for treatment-resistant depression: A retrospective multicenter real-world cohort study on effectiveness and suicidal outcomes6 months ago
- Psychological support in psychedelic-assisted therapy clinical trials: A systematic review6 months ago
- Roland R. Griffiths, psychopharmacology pioneer: Abuse liability, alcohol, nicotine, caffeine, benzodiazepines, and psychedelics6 months ago
- Pharmacological characterization of 4-F-3-Me-α-PVP: A novel synthetic cathinone with psychostimulant effects and abuse liability in rodents6 months ago
- A randomized clinical trial of repeated doses of psilocybin for the treatment of obsessive–compulsive disorder6 months ago
- Enhancement of memory network activity in schizophrenia patients by phosphodiesterase-4 (PDE4) inhibitor, roflumilast: A pilot study7 months ago
- The effects of transcranial direct current stimulation (tDCS) on subjective, autonomic and neuropsychological response in the 7.5% CO2 experimental model of anxiety7 months ago